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Other Medicines If Zovirax is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zovirax with the fo llowing:

- Cyclosporine (Sandimmune, Neoral)
- Interferon (Roferon-A)
- Probenecid (Benemid)
- Zidovudine (Retrovir)

Possible Side Effect Although side effects from Zovirax are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- burning, stinging, itching, or rash when ointment is applied
- headache
- upset stomach
- vomiting
- diarrhea or loose stools
If you experience any of the following symptoms, call your doctor immediately:

- severe rash
- severe itching
- fever
- confusion
- yellowness of the skin or eyes
- blood in the urine
- stomach pain

What Is It Zovirax is used to treat herpes infections of the skin, lip, and genitals; herpes zoster (shingles); and chickenpox. It does not cure herpes infections but decreases pain and itching and promotes heal ing.

Topical Zovirax does not prevent the recurrence of sores but may decrease pain and itching if applied when the earliest symptoms first appear. Oral Zovirax decreases the frequency and se verity of recurrent sores, but it is used only by people with severe herpes infections because of possible adverse effects.

Precautions Before Using This Medicine Pregnancy—Topical Zovirax has not been studied in pregnant women. However, this medicine has not been shown to cause birth defects or other problems in animal studies using mice, rats, or rabbits, ex ept when given in very high doses in a study using rats.

Breast-feeding—It is not known whether topical Zovirax passes into the breast milk. However, Zovirax ointment has not been reported t cause problems in nursing babies, even though small amounts of topical Zovirax are absorbed through the mother's skin and mucous membranes. Although most medicines pass into breast milk in small amou nts, many of them may be used safely while breast-feeding.

How to Use Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.

Zovirax is best used as soon as possi ble after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.

If you are taking Zovirax for the treatment of chickenpox , it is best to start taking Zovirax as soon as possible after the first sign of the chickenpox rash, usually within one day.

Zovirax capsules, tablets, and oral suspension may be taken with meals or on an empty s tomach.

Cautions This medication should be used cautiously during pregnancy only if clearly needed. It is not known if this medication appears in breast milk. Consult with your doctor before breast-feeding.
Avoid s exual activity while signs and symptoms of genital herpes are present to prevent infecting your partner. Inform your doctor if this medication does not appear to decrease the frequency or severity of recurrent infections.

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