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Cautions
.For patients with diabetes: Weight loss may result in an improvement in your condition, and your doctor may need to change your dose of oral diabetes medicine or insulin.

Visit your doctor on a regular basis to check your progressto make sure that this medicine is working properly and to check for unwanted effects

How should this medicine be used?
Xenical prevents the absorption of some of the fat you eat. Therefore, you should take it during the meal or within 1 hour of eating. If you occasionally miss a meal or eat a meal that contains no fat , you should skip the dose of Xenical.

Because Xenical may decrease the amount of some vitamins that your body can absorb from food, you will need to take a multivitamin supplement once a da y. Take the vitamin supplement at least 2 hours before or after taking Xenical

Possible food and drug interactions when taking this medication
If Xenical is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Xenical with the fo llowing:

- Cyclosporine (Neoral and Sandimmune)
- Warfarin (Coumadin)

special dietary instructions
To help you get started on reducing the fat in your diet to about 30%, read the labels on all the foods you buy. While you are taking Xenical, you should avoid foods that have more than 30% fat. When eating meat, poultry (chicken) or fish, eat only 2 or 3 ounces (about the size of a deck of cards). Choose lean cuts of meat and remove the skin from poultry. Fill up your meal plate with more grains, fruits, and vegetables. Replace whole-milk products with nonfat or 1% milk and reduced- or low-fat dairy items. Cook with less fat. Use vegetable oil spray when cooking. Salad dressings; many baked i tems; and prepackaged, processed, and fast foods are usually high in fat. Use the low- or non-fat versions of these foods and/or cut back on serving sizes.

Possible Side Effect
The most common side effect of Xenical is changes in bowel movement (BM) habits. This generally occurs during the first weeks of treatment; however, it may continue throughout your use of Xenical. Tel l your doctor if any of these symptoms are severe or do not go away:

- oily, spotting BMs
- gas with discharge
- urgent need to have a BM
- oily or fatty stools
- an oily discharge
- increased number of BMs
- inability to control BMs
- orange or brown color of a BM
- stomach pain
-

If you experience any of the following symptoms, cal l your doctor immediately:

- itching
- redness of skin
- skin rash or hives
- swelling
- chest pain
- difficulty breathing
- fever

Overdosage
The results of a massive overdose of Xenical are unknown, although the drug seems relatively harmless. However, any medication taken in excess can have serious consequences. If you suspect an overdose , seek medical attention.


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