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Ephedra's main active medical ingredients are the alkaloids ephedrine and pseudoephedrine. The ephedras also contain various tannins and related chemicals.The stem contains 1-3% total alkaloids, with ephedrine accounting for 30-90% of this total. The concentrations of these alkaloids depends upon the particular species of ephedra used.
Ephedrine is an adrenergic drug that works by stimulating alpha
-and beta receptors thus causing the release of norepinephrine.
-Alpha and beta receptors exist in the sympathetic nervous system,
-(fight or flight) and stimulation causes increased heart rate,
-bronchodilation, and vasoconstriction.
The Texas Department of Health (TDH), has proposed banning certain ephedra and ephedrine-containing products made by dietary supplement companies, while preserving products of the pharmaceutical indus try. This interesting--if a bit convoluted--proposal seeks to make the following changes in regulating products in the state of Texas:
-All ephedrine products would become prescription drugs, exce pt:
-Ephedra (ma huang) products would be exempt only if they are less than 3% alkaloid (read "NO EXTRACTS").
-It would be illegal to sell any ephedra or ephedrine-containing product in combin ation with combinations with caffeine or caffeine-containing plants including cola, tea or guarana.
-A list of over-the-counter (OTC) drugs made by pharmaceutical companies would be specifically e
Ephedrine is a naturally occuring central nervous system stimulant obtained
-from the plant _Ephedra equisetina_. It is now also produced by chemical
-synthesis, the synthetic product being mark eted in the form of its salt,
-ephedrine sulfate; it occurs as a white crystalline powder with a bitter
-taste, soluble in water and very soluble in alcohol. Ephedrine is closely
-related in structure to methamphetamine, although its CNS actions are much
-less potent and also longer-acting than those of the amphetamines. Its
-peripheral stimulant actions are similar to but less powe rful than those of
-epinephrine (also called adrenaline), a hormone produced in the body by the
-adrenal glands.
Rather than purchasing it through mail order, you might want to
-ask the local pharmicist for Ephedrine sulfate in the 100 capsule
-bottles as it's much cheaper that way. Though more difficult to find,
-ephedrine is kept as a 'behind-the-counter' drug. Legal to purchase
-without a Rx, but not put out on display.
-Ephedrine taken with caffeine is a more pleasant stimulant combinatio n
-however be aware of the warnings concerning adrenergic drugs, which you
-can discuss with someone qualified and licensed to do so.
Since early 1990, the FDA has issued numerous warnings to consumers of diet products and supplements containing Ephedrine, Ephedra or Ma Huang. In fact, in November 1994, the FDA informed Alliance U.S .A. that its Nature¡¦s Nutritional Formula One posed a potential health hazard and was in violation of federal laws designed to protect the public health and even issued a recall of their products due to their combination of Ma Huang and caffeine containing Kola Nut. Alliance later removed the caffeine containing Kola Nut and was allowed to continue to sell its new product.


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