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Ephedrine is the oral form of Epinephrine, or adrenaline. It was
-once a commonly prescribed drug for asthma, but newer drugs in the
-xanthine class have less side effects.
-Ephedrine is rela
ted to pseudoephedrine which was designed as a
-decongestant with less undesirable effects.
-Ephedra is a Chinese herb that's been used for centuries to treat
-asthma
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The Texas Department of Health (TDH), has proposed banning certain ephedra and ephedrine-containing products made by dietary supplement companies, while preserving products of the pharmaceutical indus
try. This interesting--if a bit convoluted--proposal seeks to make the following changes in regulating products in the state of Texas:
-All ephedrine products would become prescription drugs, exce
pt:
-Ephedra (ma huang) products would be exempt only if they are less than 3% alkaloid (read "NO EXTRACTS").
-It would be illegal to sell any ephedra or ephedrine-containing product in combin
ation with combinations with caffeine or caffeine-containing plants including cola, tea or guarana.
-A list of over-the-counter (OTC) drugs made by pharmaceutical companies would be specifically e
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Ephedra's main active medical ingredients are the alkaloids ephedrine and pseudoephedrine. The ephedras also contain various tannins and related chemicals.The stem contains 1-3% total alkaloids, with
ephedrine accounting for 30-90% of this total. The concentrations of these alkaloids depends upon the particular species of ephedra used.
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Ephedrine is a naturally occuring central nervous system stimulant obtained
-from the plant _Ephedra equisetina_. It is now also produced by chemical
-synthesis, the synthetic product being mark
eted in the form of its salt,
-ephedrine sulfate; it occurs as a white crystalline powder with a bitter
-taste, soluble in water and very soluble in alcohol. Ephedrine is closely
-related in
structure to methamphetamine, although its CNS actions are much
-less potent and also longer-acting than those of the amphetamines. Its
-peripheral stimulant actions are similar to but less powe
rful than those of
-epinephrine (also called adrenaline), a hormone produced in the body by the
-adrenal glands.
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Higher doses (overdose)
-can cause restlessness and anxiety, dizziness, insomnia, tremor, rapid
-pulse, sweating, respiratory difficulties, confusion, hallucinations,
-delerium, and (very inf
requently) convulsions. The most dangerous symptoms
-of overdose are abnormally high blood pressure and rapid, irregular
-heartbeat. A dose of ephedrine only two to three times the theraputic
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Ephedrine act as stimulants that can cause rapid or irregular heartbeats (heart arrhythmias) Ephedrines act in a similar way as that of adrenaline. It dilates the bronchial muscles, contacts the nasal
mucosa, raises the blood pressure and is a cardiac stimulant. Further these compounds often cause psychological side effects such as depression, nervousness, insomnia, and rapid heart rate. When take
n in combination with caffeine, ephedrine can over-stimulate the central nervous system, leading to potentially life-threatening results.
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