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Drug Interactions
If you are taking Valtrex with certain other drugs, the effect of either drug could be increased, decreased, or altered. Check with your doctor before combining Valtrex with cimetidine (Tagamet) and/o r probenecid (Benemid).

Symptoms of overdose may include:
When taken by people with kidney disorders, excessive doses of Valtrex have been known to cause psychological problems and kidney failure. If you suspect an overdose, check with your doctor immediatel y.

What side effects can this medication cause?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Valtrex.

Side effects may include:
- Abdominal pain, aggressive behavior, agitation, allergic reactions, coma, confusion, decreased consciousness, depression, diarrhea, dizziness, facial swelling, ha llucinations, headache, hepatitis, high blood pressure, joint pain, mania, menstrual problems, nausea, rapid heartbeat, rash, visual abnormalities, vomiting

Before Taking This Medicine
Pregnancy¡XAdequate and well-controlled studies in humans have not been done with Valtrex or acyclovir. However, acyclovir has been used in pregnant women and has not been reported to cause birth defe ts or other problems.

What special precautions should I follow?
The presence of other medical problems may affect the use of Valtrex. Make sure you tell your doctor if you have any other medical problems, especially:
- Advanced human immunodeficiency virus (H IV) infection or
- Bone marrow transplantation or
- Kidney transplantation¡XPatients with these medical problems may have an increased risk of severe side effects
- Kidney disease¡XKidn disease may increase blood levels of this medicine, increasing the chance of side effects

How to Use
If you are taking Valtrex for shingles, you should start using it as soon as possible after your doctor has made a diagnosis. It's best to see a doctor and start the drug within 48 hours of first noti cing the rash. If you wait more than 72 hours after you first get a herpes zoster rash, the medication may not be effective.

If you are using Valtrex for genital herpes, begin taking it at t he first sign of an attack. The medication may not be effective if you wait longer than 72 hours after the first attack or 24 hours after a later attack.

If you are taking Valtrex for cold s ores, you should start using it at the earliest signs of infection, such as tingling, itching, or burning.


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