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Drug Interactions When you are taking Sonata, it is especially important that your health care professional know if you are taking any of the following:

- Rifampin (e.g., Rifadin)—These medicines may decrea e the effectiveness of Sonata
- Cimetidine (e.g., Tagamet)—Cimetidine may interfere with the breakdown of Sonata in the body, possibly leading to unwanted effects
- Other central nervous s tem (CNS) depressants (medicines that cause drowsiness) or
- Tricyclic antidepressants (medicine for depression)—The CNS depressant effects of either these medicines or Sonata may be increased, ossibly leading to unwanted effects

Precautions Before Using This Medicine Breast-feeding—Sonata passes into breast milk, but the effect on nursing babies is unknown

Other medical problems The presence of other medical problems may affect the use of Sonata. Make sure to tell your doctor if you have any other medical problems, especially
- Alcohol abuse (or history of) or
- Drug abuse or dependence (or history of)— Dependence on Sonata may develop
- Breathing problems or
- Mental depression—Sonata may make the condition worse
- Liver disease— Higher blood ls of Sonata may result, increasing the chance of side effects.

What is this Drug Sonata belongs to the group of medicines called central nervous system (CNS) depressants (medicines that make you drowsy or less alert). Sonata is used to treat insomnia (trouble sleeping). In general , when sleep medicines are used every night for a long time, they may lose their effectiveness. In most cases, sleep medicines should be used only for short periods of time, such as 1 or 2 days, and g enerally for no longer than 1 or 2 weeks.

What side effects may occur? Although side effects from Sonata are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- drowsiness
- dizziness
- lightheadedness
- lack of coordination
- headache
- constipation
- dry mouth
- muscle aches

If you experience any of the following symptoms, call your doctor immediately:

- skin rash
- itching
- fast or irregular heartbeat
- chest pain
- difficulty breathing
- fever
- behavior changes or acting differently
- mental confusion
- a bnormal thinking or dreams
- hallucinations
- depression
- worsening of insomnia
- problems with memory

What special precautions should I follow? If you will be taking Sonata for a long time, do not stop taking it without first checking with your doctor. Your doctor may want you to reduce gradually the amount you are taking before stopping comp letely. Stopping this medicine suddenly may cause withdrawal side effects.

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