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Precautions Before Using This Medicine
Breast-feeding¡XIt is not known whether Retin-A passes into the breast milk. Mothers who are using this medicine and who wish to breast-feed should discuss this with their doctors.

Possible Side Effect
In some animal studies, Retin-A has been shown to cause skin tumors to develop faster when the treated area is exposed to ultraviolet light (sunlight or artificial sunlight from a sunlamp). Other stud ies have not shown the same result and more studies need to be done. It is not known if Retin-A causes skin tumors to develop faster in humans.

Check with your doctor as soon as possible if a ny of the following side effects occur:

- Burning feeling or stinging skin (severe); lightening of skin of treated area, unexpected; peeling of skin (severe); redness of skin (severe) ; u nusual dryness of skin (severe)

- Darkening of treated skin

Other Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is t o be applied to the same area of the skin. When you are using topical Retin-A, it is especially important that your health care professional know if you are taking any of the following:

- Ac itretin (e.g., Soriatane)
- Etretinate (e.g., Tegison)
- Retin-A, oral ¡XMay increase chance of getting severe dryness or redness of skin

Why is this medication prescribed?
For patients using Retin-A for the treatment of acne:
- Regular use of water-based creams or lotions helps to reduce skin irritation or dryness that may be caused by the use of Retin-A.
For patients using Retin-A for the treatment of fine wrinkling, dark spots, and rough skin caused by the sun:
- This medicine should be used as part of an ongoing program to avoid further damage to y our skin from the sun. This program includes staying out of the sun when possible or wearing proper clothing or hats to protect your skin from sunlight.
- Regular use of oil-based creams or lotio ns helps to reduce skin irritation or dryness caused by the use of Retin-A.

Special warnings about this medication
During the first 6 months of use, avoid overexposing the treated areas to sunlight, wind, or cold weather. The skin will be more prone to sunburn, dryness, or irritation, especially during the first 2 or 3 weeks. However, you should not stop using this medicine unless the skin irritation becomes too severe. Do not use a sunlamp .

Why is this medication prescribed?
Retin-A comes in topical liquid, cream, and gel. Retin-A usually is used daily at bedtime or once every 2 or 3 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Retin-A exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.


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