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Possible Side Effect Although side effects from Retin-A are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- warmth or slight stinging of the skin
- ligh tening or darkening of the skin
- red, scaling skin
- increase in acne sores
- swelling, blistering, or crusting of the skin

Precautions while Using this Medicine To help Retin-A work properly, regularly use sunscreen or sunblocking lotions with a sun protection factor (SPF) of at least 15. Also, wear protective clothing and hats, and apply creams, lotions, or moisturizers often.

What is this Drug Retin-A is used to treat acne. It works partly by keeping skin pores clear.

One of the Retin-A creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by damaging rays of the sun. It works by lightening the skin, replacing older skin with newer skin, and by slowing down the way the body removes skin cells that may have been harmed by the sun. Retin-A works bes t when used within a skin care program that includes protecting the treated skin from the sun. However, it does not completely or permanently erase these skin problems or greatly improve more obvious changes in the skin, such as deep wrinkles caused by sun or the natural aging process.

Description Your acne probably will get worse (red, scaling skin and an increase in acne sores) during the first 7-10 days that you use this medication. Nevertheless, continue to use it; the acne sores should dis appear. Usually 2-3 weeks (and sometimes more than 6 weeks) of regular use of Retin-A is required before improvement is seen.

Before Taking This Medicine Older adults—Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause differ nt side effects or problems in older people. There is no specific information comparing use of Retin-A in patients 50 years of age and older with use in other age groups.

Other Medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is t o be applied to the same area of the skin. When you are using topical Retin-A, it is especially important that your health care professional know if you are taking any of the following:

- Ac itretin (e.g., Soriatane)
- Etretinate (e.g., Tegison)
- Retin-A, oral —May increase chance of getting severe dryness or redness of skin

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