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Symptoms of overdose
Nausea and vomiting were prominent in overdoses involving higher fluoxetine doses. Other prominent symptoms of overdose included agitation, restlessness, hypomania, and other signs of CNS excitation,
including seizures.
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Possible food and drug interactions
Combining Prozac with MAO inhibitors or Mellaril (thioridazine) is dangerous.
Do not drink alcohol while taking this medication.
It is especially important to check with your docto
r before combining Prozac with the following:
- Alprazolam (Xanax)
- Carbamazepine (Tegretol)
- Clozapine (Clozaril)
- Diazepam (Valium)
- Digitoxin (Crystodigin)
-
Drugs that impair brain function, such as sleep aids and narcotic painkillers
- Flecainide (Tambocor)
- Haloperidol (Haldol)
- Lithium (Eskalith)
- Other antidepressants (Elavil) <
br> - Phenytoin (Dilantin)
- Pimozide (Orap)
- Tryptophan
- Vinblastine (Velban)
- Warfarin (Coumadin)
|
Special Wanring
Allergic or Toxic:
Frequent: Rash, pruritus.
Infrequent: Chills and fever, urticaria, maculopapular rash.
Rare: Allergic reaction, erythema multiforme, vesiculobullous rash, se
rum sickness, contact dermatitis, erythema nodosum, purpuric rash, leukocytoclastic vasculitis, leukopenia, thrombocythemia, arthralgia, angioedema, bronchospasm, lung fibrosis, allergic alveolitis, l
arynx edema, respiratory distress.
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Drug Interactions
Venlafaxine (e.g., Effexor)¡XUsing these medicines with fluoxetine or within 5 weeks of stopping fluoxetine may increase the chance of developing a rare, but very serious, unwanted effect known as the
serotonin syndrome. This syndrome may cause confusion, diarrhea, fever, poor coordination, restlessness, shivering, sweating, talking or acting with excitement you cannot control, trembling or shaking
, or twitching. If you develop these symptoms contact your doctor as soon as possible. Taking tramadol with fluoxetine increases the chance of having convulsions (seizures). Also, taking tryptophan wi
th fluoxetine may result in increased agitation or restlessness and intestinal or stomach problems
|
Precautions
Hyponatremia: - Several cases of hyponatremia (some with serum sodium lower than 110 mmol/L) have been reported. The hyponatremia appeared to be reversible when fluoxetine was discontinued. Although t
hese cases were complex with varying possible etiologies, some were possibly due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). The majority of these occurrences have been in
older patients and in patients taking diuretics or who were otherwise volume depleted.
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Why is this medication prescribed?
In addition, Prozac is used to treat panic disorder, including panic associated with agoraphobia (a severe fear of being in crowds or public places). People with panic disorder usually suffer from pan
ic attacks--feelings of intense fear that develop suddenly, often for no reason. Various symptoms occur during the attacks, including a rapid or pounding heartbeat, chest pain, sweating, trembling, an
d shortness of breath.
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