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Precautions Before Using This Medicine
Older adults¡XMany medicines have not been tested in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effec
s or problems in older people. In studies done to date that included elderly people, Prozac did not cause different side effects or problems in older people than it did in younger adults.
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Other Medicines
Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate])¡X Do
ot take fluoxetine while you are taking or within 2 weeks of taking an MAO inhibitor. If you do, you may develop confusion, agitation, restlessness, stomach or intestinal problems, sudden high body te
mperature, extremely high blood pressure, and severe convulsions. At least 14 days should be allowed between stopping treatment with an MAO inhibitor and starting treatment with fluoxetine.
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Symptoms of overdose
Any medication taken in excess can have serious consequences. An overdose of Prozac can be fatal. In addition, combining Prozac with certain other drugs can cause symptoms of overdose. If you suspect
an overdose, seek medical attention immediately.
Common symptoms of Prozac overdose include:
Nausea, rapid heartbeat, seizures, sleepiness, vomiting
Other symptoms of Prozac ov
erdose include:
Coma, delirium, fainting, high fever, irregular heartbeat, low blood pressure, mania, rigid muscles, sweating, stupor
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Adverse Effects
Commonly Observed: - In clinical trials, the most commonly observed adverse events associated with the use of fluoxetine and not seen at an equivalent incidence among placebo treated patients were: CN
S complaints, including headache, nervousness, insomnia, drowsiness, fatigue or asthenia, anxiety, tremor, and dizziness or lightheadedness; gastrointestinal complaints, including nausea, diarrhea, dr
y mouth and anorexia; and excessive sweating.
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Precautions
Seizures:
Fluoxetine should be used with caution in patients with a history of convulsive disorders. The incidence of seizures associated with fluoxetine during clinical trials did not appear to d
iffer from that reported with other marketed antidepressants; however, patients with a history of convulsive disorders were excluded from these trials.
Concurrent administration with electro
shock therapy should be avoided because of the absence of experience in this area. There have been rare reports of a prolonged seizure in patients on fluoxetine receiving ECT treatment.
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Proper Use of This Medicine
Prozac comes as a capsule, tablet, and liquid to take by mouth. It is usually taken once or twice a day and may be taken with or without food. Follow the directions on your prescription label carefull
y, and ask your doctor or pharmacist to explain any part you do not understand. Take Prozac exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Continue to take Prozac even if you feel well. Do not stop taking Prozac without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will want
to decrease your dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt.
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