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Possible food and drug interactions when taking this medication
When you are taking Prozac, it is especially important that your health care professional know if you are taking any of the following:

- Astemizole (e.g., Hismanal)¡XHigher blood levels of a temizole may occur, which increases the chance of having a very serious change in the rhythm of your heartbeat
- Buspirone (e.g., BuSpar) or
- Bromocriptine (e.g., Parlodel) or
- Dextro methorphan (cough medicine) or
- Levodopa (e.g., Sinemet) or
- Lithium (e.g., Eskalith) or
- Meperidine (e.g., Demerol) or
- Nefazodone (e.g., Serzone) or
- Pentazocine (e.g., Talwin) or

Drug Interactions
Combining Prozac with MAO inhibitors or Mellaril (thioridazine) is dangerous.

Do not drink alcohol while taking this medication.

It is especially important to check with your docto r before combining Prozac with the following:

- Alprazolam (Xanax)
- Carbamazepine (Tegretol)
- Clozapine (Clozaril)
- Diazepam (Valium)
- Digitoxin (Crystodigin)
- Drugs that impair brain function, such as sleep aids and narcotic painkillers
- Flecainide (Tambocor)
- Haloperidol (Haldol)
- Lithium (Eskalith)
- Other antidepressants (Elavil) < br> - Phenytoin (Dilantin)
- Pimozide (Orap)
- Tryptophan
- Vinblastine (Velban)
- Warfarin (Coumadin)


What side effects can this medication cause?
Check with your doctor as soon as possible if any of the following side effects occur:

- difficulty in concentration, drowsiness, excessive hunger, fast heartbeat, headache, shakiness or unst eady walk, or unusual tiredness or weakness; symptoms of hyponatremia (low blood sodium), including confusion, convulsions (seizures), drowsiness, dryness of mouth, increased thirst, lack of energy; symptoms of serotonin syndrome, including diarrhea, fever, increased sweating, mood or behavior changes, overactive reflexes, racing heartbeat, restlessness, shivering or shaking; talking, feeling, and acting with excitement and activity you cannot control; trouble in breathing; unusual or incomplete body or facial movements;

Precautions
Concomitant Illness: - Clinical experience with fluoxetine in patients with concomitant systemic illness is limited and it should be used cautiously in such patients, especially those with diseases or conditions that could affect metabolism or hemodynamic responses


Special Wanring
Serious, sometimes fatal, reactions have been known to occur when Prozac is used in combination with other antidepressant drugs known as MAO inhibitors, including Nardil and Parnate; and when Prozac i s discontinued and an MAO inhibitor is started. Never take Prozac with one of these drugs or within at least 14 days of discontinuing therapy with one of them; and allow 5 weeks or more between stoppi ng Prozac and starting an MAO inhibitor. Be especially cautious if you have been taking Prozac in high doses or for a long time.

If you are taking any prescription or nonprescription drugs, notify your doctor before taking Prozac.

What is this medicine
Prozac is a member of the family of drugs called "selective serotonin re-uptake inhibitors." Serotonin is one of the chemical messengers believed to govern moods. Ordinarily, it is quickly reabsorbed after its release at the junctures between nerves. Re-uptake inhibitors such as Prozac slow this process, thereby boosting the levels of serotonin available in the brain.



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