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Other Medicines
Renal Impairment: - Since paroxetine is extensively metabolized by the liver, excretion of unchanged drug in urine is a minor route of elimination. However, single dose pharmacokinetic studies in subj
ects with clinically significant renal impairment suggest that plasma levels of paroxetine are elevated in such subjects. Paroxetine should therefore be used with caution and the dosage restricted to
the lower end of the range in patients with clinically significant renal impairment.
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What Is It
Paxil is used to treat depression, obsessive-compulsive disorders, panic attacks, social anxiety disorder, generalized anxiety disorder, and posttraumatic stress disorder. Paxil controlled-release (P
axil CR) is used to treat depression and panic attacks. Paxil is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amounts of certain natural
substances in the brain.
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Overdose
Overdose attempts have been reported with paroxetine; up to 850 mg alone and in combination with other agents. In cases where paroxetine was used alone, no deaths have occurred and recovery was medica
lly uneventful.
Symptoms of overdosage with paroxetine include nausea, vomiting, tremor, dilated pupils, dry mouth and irritability. There are no reports of ECG abnormalities, coma or convul
sions following overdosage with paroxetine alone.
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Precautions while Using this Medicine
Before taking Paxil,
remember that alcohol can add to the drowsiness caused by this drug.
tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness o
f this drug.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Paxil may make your skin sensitive to sunlight.
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Precautions Before Using This Medicine
Children¡XPaxil has not be shown to be safe and effective in children or adolescents, 18 years of age or younger. Children may be especially sensitive to the effects of Paxil for the treatment of depr
ssion. This may increase the chance of a child planning to commit suicide or attempting to commit suicide. Talk to your doctor about the risks and benefits of taking this medication.
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What side effects can this medication cause?
Rare side effects may include:
- Abnormal thinking, acne, alcohol abuse, allergic reaction, asthma, belching, blood and lymph abnormalities, breast pain, bronchitis, chills, colitis, difficulty s
wallowing, dry skin, ear pain, exaggerated sense of well-being, eye pain or inflammation, face swelling, fainting, generally ill feeling, hair loss, hallucinations, heart and circulation problems, hig
h blood pressure, hostility, hyperventilation, increased salivation, increased sex drive, inflamed gums, inflamed mouth or tongue, lack of emotions, menstrual problems, migraine, movement disorders, n
eck pain, nosebleeds, paranoid and manic reactions, poor coordination, respiratory infections, sensation disorders, shortness of breath
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