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Special warnings about this medication
Before taking .Imitrex,

- tell your doctor and pharmacist if you are allergic to .Imitrex or any other drugs.
- tell your doctor if you are pregnant, plan to become pregnant, or are brea st-feeding. If you become pregnant while taking .Imitrex, call your doctor.
- you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this d rug affects you.
- remember that alcohol can add to the drowsiness caused by this drug.

Significant Interactions:
Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine, especially other prescription medicine for migraine headaches, or if y ou smoke tobacco.

When you are taking .Imitrex, it is especially important that your health care professional know if you are taking the following:

Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate])¡XTaking .Imitrex while you are taking r within 2 weeks of taking MAO inhibitors may cause sudden high body temperature, extremely high blood pressure and severe convulsions;

Precautions Before Using This Medicine
Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to .Imitrex. Also tell your health care professional if you are allergic to any other substances, such as foods, prese vatives, or dyes.

Description
.Imitrex injection is also used to treat cluster headaches.

.Imitrex has caused serious side effects in some people, especially people who have heart or blood vessel disease. Be sure that you discuss with your doctor the risks of using this medicine as well as the good that it can do.

Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Imitrex overdose may include:
- Bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor

Possible Side Effect
If you develop severe chest pain, call the doctor immediately. Also seek immediate attention if you suffer sudden, severe abdominal pain after a dose of Imitrex. It could signal a blood vessel problem .

Be careful not to inject Imitrex into a vein. This can cause a serious heart irregularity.

If your fingers turn pale, then blue, after a dose of Imitrex, you may have a circulato ry problem such as hardening of the arteries. Be sure to let your doctor know.

This medication should not be used for other types of migraine headache. If the first dose does not relieve you r symptoms, your doctor will re-evaluate you; you may not have migraine or cluster headache.


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