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What side effects may occur?
Although side effects from acetaminophen, butalbital, and caffeine are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- drowsiness
- upset stomach
- vomiting
- stomach pain
- depression
- lightheadedness
- confusion

If you experience any of the following symptoms, call your doctor immediately:
- skin rash
- itching
- difficulty breathing

Symptoms of overdose may include:
Seek emergency medical attention. Symptoms of an acetamino phenbutalbita lcaffeine - Esgic overdose include insomnia, restlessness, tremor, nausea, vomiting, diarrhea, abdominal pain, sweating, seizur es, drowsiness, decreased breathing,

How to Use
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If butalbital and acetaminophen co mbination is taken regularly (for example, every day), it may become habit-forming (causing mental or physical dependence). The caffeine in some butalbital and acetaminophen combinations can also incr ease the chance of dependence. Dependence is especially likely to occur in patients who take these medicines to relieve frequent headaches. Taking too much of this medicine may also lead to liver dama ge or other medical problems.

Why is this medication prescribed?
Some butalbital and acetaminophen combinations also contain caffeine (KAF-een) . Caffeine may help to relieve headaches. However, caffeine can also cause physical dependence when it is used for a long time. This may lead to withdrawal (rebound) headaches when you stop taking it.

Butalbital and acetaminophen combination may also be used for other kinds of headaches or other kinds of pain a s determined by your doctor.

Missed Dose
Take the missed dose as soon as you remember. Do not takedouble dose of Esgic . Wait the prescribed amount of time before taking your next dose.

Precautions Before Using This Medicine
Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol abuse or
- Drug abuse or dependence¡XDependence on butalbital may develop; also, acetaminophen ma cause liver damage in people who abuse alcohol
- Asthma, emphysema, or other chronic lung disease or
- Hepatitis or other liver disease or
- Hyperactivity (in children) or
- Kidne y disease¡XThe chance of serious side effects may be increased
- Diabetes mellitus (sugar diabetes) or
- Mental depression or
- Overactive thyroid or
- Porphyria¡XButalbital can ma these conditions worse
- Heart disease (severe)¡XThe caffeine in some butalbital and acetaminophen combinations can make some kinds of heart disease worse


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