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Proper Use of This Medicine
Fluconazole comes as a tablet and liquid to take by mouth. It is usually taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fluconazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

Continue to take fluconazole even if you feel well. Do not stop taking fluconazole without talking to your doctor.

Other medical problems
Pregnancy¡XStudies have not been done in pregnant women. However, studies in some animals have shown that Diflucan, taken in high doses, may cause harm to the mother and the fetus. They have caused bi th defects in animals. Before taking these medicines, make sure your doctor knows if you are pregnant or if you may become pregnant.Breast-feeding¡XDiflucan pass into breast milk. Mothers who are taki g these medicines and who wish to breast-feed should discuss this with their doctors.

Cautions
If you are taking antacids, cimetidine (e.g., Tagamet), famotidine (e.g., Pepcid), nizatidine (e.g., Axid), omeprazole (e.g., Prilosec), or ranitidine (e.g., Zantac) while you are taking itraconazole or ketoconazole, take the other medicine at least 2 hours after you take itraconazole or ketoconazole . If you take these medicines at the same time that you take itraconazole or ketoconazole, they wi ll keep your antifungal medicine from working properly.

Possible food and drug interactions when taking this medication
If Diflucan is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Diflucan with the following:

- Blood-thinning drugs such as Coumadin
- Antidiabetic drugs such as Orinase, DiaBeta, and Glucotrol
- Astemizole (Hismanal)
- Cisapride (Propulsid)
- Cyclospo rine (Sandimmune, Neoral)
- Hydrochlorothiazide (HydroDIURIL)
- Phenytoin (Dilantin)
- Rifabutin (Mycobutin)
- Rifampin (Rifadin)
- Tacrolimus (Prograf)
- Terfenadine (Se ldane)
- Theophylline (Theo-Dur)
- Ulcer medications such as Tagamet

Possible Side Effect
For women taking a single dose to treat vaginal infection, the most common side effects are abdominal pain, diarrhea, headache, and nausea; changes in taste, dizziness, and indigestion may occur less often.

Less common side effects may include:
- Abdominal pain, diarrhea, headache, skin rash, vomiting

Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical treatment immediately.

Symptoms of Diflucan overdose may include:
- Hallucinations , paranoia


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