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Cautions It is important that your doctor check your progress at regular visits. This will allow your doctor to check for any unwanted effects.

If your symptoms do not improve within a few weeks (or m onths for some infections), or if they become worse, check with your doctor.

These medicines should notbe taken with astemizole (e.g., Hismanal), cisapride (e.g., Propulsid),dofetilide (e.g., Tikosyn) or terfenadine (e.g., Seldane). Doing so may increase the risk of serious side effects affecting the heart.

Side Effects Although side effects from fluconazole are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- upset stomach
- loss of appetite
- altered taste
- diarrhea or loose stools
- headache
- dizziness
- fatigue

If you experience any of the following symptoms, call your doctor immediately:

- rash
- itching
- vomiting
- yellowing of the skin or eyes
- dark urine
- pale stools

Drug Interactions When you are taking Diflucan, it is especially important that your health care professional know if you are taking any of the following:

- Phenothiazines (acetophenazine [e.g., Tindal], chlo rpromazine [e.g., Thorazine], fluphenazine [e.g., Prolixin], mesoridazine [e.g., Serentil], perphenazine [e.g., Trilafon], prochlorperazine [e.g., Compazine], promazine [e.g., Sparine], promethazine [ e.g., Phenergan], thioridazine [e.g., Mellaril], trifluoperazine [e.g., Stelazine], triflupromazine [e.g., Vesprin], trimeprazine [e.g., Temaril]) or
- Valproic acid (e.g., Depakene)—Use of thes medicines with Diflucan may increase the chance of side effects affecting the liver

How should this medicine be used? Fluconazole comes as a tablet and liquid to take by mouth. It is usually taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fluconazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

Continue to take fluconazole even if you feel well. Do not stop taking fluconazole without talking to your doctor.

What special precautions should I follow? Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to any of the Diflucan. Also tell your health care professional if you are allergic to any other substances, such as f ods, preservatives, or dyes.

Symptoms of overdose may include: Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical treatment immediately.

Symptoms of Diflucan overdose may include:
- Hallucinations , paranoia

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