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Possible Side Effect
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:
- Bloody or black tarry stools; burning feeling in chest or stomach; chills; congestion in chest; cough; diarrhea; fati gue; fever; loss of appetite; muscle aches and pains; nausea; shortness of breath; stomach pain (severe); tenderness in stomach area; unusual weight gain; vomiting of blood or material that l ooks like coffee grounds; weakness

Other Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. When you are taking celecoxib, it is especially important that your health care professional know if you are taking any of the following:
- Aspirin or
- Fluconazole (e.g., Diflucan)¡XThe chance of serious side effects may be increased
- Lithium (e.g., Lithane)¡XHigher blood levels of celecoxib and an increased chance of si effects may occur

Other medical problems
The presence of other medical problems may affect the use of celecoxib. Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol abuse or
- Bleeding probl ems or
- Stomach ulcer or other stomach or intestinal problems or
- Tobacco use (or recent history of)¡XThe chance of side effects may be increased
- Anemia or
- Asthma or
- D hydration or
- Fluid retention (swelling of feet or lower legs) or
- Heart disease or
- High blood pressure or
- Kidney disease or
- Liver disease¡XCelecoxib may make these co ditions worse

What Is It
Celebrex is a drug that helps relieve pain associated with osteoarthritis and adult rheumatoid arthritis. The reason that Celebrex has become so popular is because it is easier on the stomach than oth er anti-arthritis medication. Celebrex is used to relieve the pain, tenderness, inflammation (swelling), and stiffness caused by arthritis. This medicine is a nonsteroidal anti-inflammatory drug (NSAI D) known as a COX-2 inhibitor used to relieve the symptoms of osteoarthritis and rheumatoid arthritis in adults. Reporting on the 63rd Annual Meeting of the American College of Rheumatology in Decembe r, thirdage.com reported that in analysis of 800 arthritis patients, more than one-third had stopped taking medications because they couldn't handle the stomach pains associated with the drugs.

How should this medicine be used?
You should continue to take CELEBREX as prescribed even when you are feeling better. CELEBREX can be taken with or without food. CELEBREX capsules come in 2 strengths: 100 mg and 200 mg.

In O steoarthritis, the recommended dose for CELEBREX is 200 mg a day. CELEBREX delivers 24-hour relief from a once-daily dose of 200 mg. Or if preferred, a dose of 100 mg twice a day is available.

In Rheumatoid Arthritis, the recommended dose for CELEBREX is 100 mg to 200 mg, twice a day. CELEBREX provides relief through the day and through the night.

Overdose
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Celebrex overdose may include:
Breathing diffic ulties, coma, drowsiness, gastrointestinal bleeding, high blood pressure, kidney failure, nausea, sluggishness, stomach pain, vomiting


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