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What is this medicine
Celebrex is a drug that helps relieve pain associated with osteoarthritis and adult rheumatoid arthritis. The reason that Celebrex has become so popular is because it is easier on the stomach than oth er anti-arthritis medication. Celebrex is used to relieve the pain, tenderness, inflammation (swelling), and stiffness caused by arthritis. This medicine is a nonsteroidal anti-inflammatory drug (NSAI D) known as a COX-2 inhibitor used to relieve the symptoms of osteoarthritis and rheumatoid arthritis in adults. Reporting on the 63rd Annual Meeting of the American College of Rheumatology in Decembe r, thirdage.com reported that in analysis of 800 arthritis patients, more than one-third had stopped taking medications because they couldn't handle the stomach pains associated with the drugs.

Other Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. When you are taking celecoxib, it is especially important that your health care professional know if you are taking any of the following:
- Aspirin or
- Fluconazole (e.g., Diflucan)¡XThe chance of serious side effects may be increased
- Lithium (e.g., Lithane)¡XHigher blood levels of celecoxib and an increased chance of si effects may occur

Other medical problems
The presence of other medical problems may affect the use of celecoxib. Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol abuse or
- Bleeding probl ems or
- Stomach ulcer or other stomach or intestinal problems or
- Tobacco use (or recent history of)¡XThe chance of side effects may be increased
- Anemia or
- Asthma or
- D hydration or
- Fluid retention (swelling of feet or lower legs) or
- Heart disease or
- High blood pressure or
- Kidney disease or
- Liver disease¡XCelecoxib may make these co ditions worse

What side effects may occur?
Although side effects from celecoxib are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- water retention
- upset stomach
- sto mach pain or cramps
- diarrhea
- gas
- headache

If you experience any of the following symptoms, call your doctor immediately:

- bloody vomit
- bloody diarrhea or black, tarry stools
- ringing in the ears
- blurred vision
- swelling of the hands, feet, ankles, or lower legs
- skin rash
- itching
- yellowing of the skin or eyes < br> - unexplained weight gain


Symptoms of overdose may include:
Bloody or black, tarry stools; continuing thirst; dizziness; drowsiness ; headache, severe or continuing; nausea and/or vomiting; shortness of breath; stomach pain; sudden decrease in the amou nt of urine; swelling of face, fingers, and/or lower legs; tightness in chest and/or wheezing; troubled breathing; unusual tiredness or weakness; vomiting of blood or material that looks like cof fee grounds; weight gain
- lack of energy
- drowsiness
- upset stomach
- vomiting
- stomach pain

Proper Use of This Medicine
Celecoxib comes as a capsule to take by mouth. It is usually taken once or twice a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any par t you do not understand. Take celecoxib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.


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