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Why is this medication prescribed?
Celebrex is prescribed for acute pain, menstrual cramps, and the pain and inflammation of osteoarthritis and rheumatoid arthritis. It is the first of a new class of nonsteroidal anti-inflammatory drug
s (NSAIDs) called "COX-2 inhibitors." Like older NSAIDs such as Motrin and Naprosyn, Celebrex is believed to fight pain and inflammation by inhibiting the effect of a natural enzyme called COX-2. Unli
ke the older medications, however, it does not interfere with a similar substance, called COX-1, which exerts a protective effect on the lining of the stomach. Celebrex is therefore less likely to cau
se the bleeding and ulcers that sometimes accompany sustained use of the older NSAIDs.
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Before Using This Medicine
Before taking celecoxib,
- tell your doctor and pharmacist if you are allergic to celecoxib, aspirin or other nonsteroidal anti-inflammatory drugs, sulfas, or any other drugs.
- tell your doc
tor if you have or have ever had liver, heart, or kidney disease; high blood pressure; asthma; any stomach problems including ulcers or bleeding; or any other gastrointestinal disease.
- tell you
r doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking celecoxib, call your doctor.
- if you are having surgery, including dental surger
y, tell the doctor or dentist that you are taking celecoxib
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How to Use
Celecoxib comes as a capsule to take by mouth. It is usually taken once or twice a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any par
t you do not understand. Take celecoxib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
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Possible food and drug interactions when taking this medication
Include on your medical history/personal profile all of the other medicines you are taking or plan to take while you are on CELEBREX, even other medicines that you can get without a prescription. CELE
BREX has significant drug interactions with :
- Methotrexate (a medicine used to suppress the immune system).
- Warfarin (a blood thinner).
- Rifampin (an antibiotic).
<
br> - ACE inhibitors (medicines used for high blood pressure and heart failure).
- Lithium (a medicine used to treat a certain type of depression).
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Symptoms of overdose may include:
Bloody or black, tarry stools; continuing thirst; dizziness; drowsiness ; headache, severe or continuing; nausea and/or vomiting; shortness of breath; stomach pain; sudden decrease in the amou
nt of urine; swelling of face, fingers, and/or lower legs; tightness in chest and/or wheezing; troubled breathing; unusual tiredness or weakness; vomiting of blood or material that looks like cof
fee grounds; weight gain
- lack of energy
- drowsiness
- upset stomach
- vomiting
- stomach pain
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Side Effects
Although side effects from celecoxib are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:
- water retention
- upset stomach
- sto
mach pain or cramps
- diarrhea
- gas
- headache
If you experience any of the following symptoms, call your doctor immediately:
- bloody vomit
- bloody diarrhea
or black, tarry stools
- ringing in the ears
- blurred vision
- swelling of the hands, feet, ankles, or lower legs
- skin rash
- itching
- yellowing of the skin or eyes <
br> - unexplained weight gain
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