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Drug Interactions
In laboratory studies in healthy volunteers, buspirone in doses up to 20 mg did not potentiate the psychomotor impairment produced by relatively modest doses of alcohol. However, decreased contentedne
ss or dysphoria was observed with a combination of alcohol and a 20 mg single dose of buspirone. Since no data are available on concomitant use of higher doses of buspirone and alcohol, it is prudent
to advise patients to avoid alcohol during buspirone therapy.
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What is this medicine
BUSPAR differs from typical benzodiazepines like Vallium or Xanax anti-anxiety medication in that it does not exert anti-seizure or muscle relaxant effects. It also lacks the prominent sedative effect
that is associated with benzodiazepines. In vitro studies have shown that BUSPAR has a high affinity for serotonin receptors (receptors in the brain that mediate arousal). BUSPAR has no significant a
ffinity for benzodiazepine receptors in the brain.
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Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose of BuSpar, seek medical attention immediately.
The symptoms of BuSpar overdose may include:
- Di
zziness, drowsiness, nausea or vomiting, severe stomach upset, unusually small pupils.
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Precautions
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For buspirone, the following should be co
nsidered:
Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to buspirone. Also tell your health care professional if you are allergic to any other substances,
uch as foods, preservatives, or dyes.
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What side effects can this medication cause?
More common side effects may include:
- Dizziness, dry mouth, fatigue, headache, light-headedness, nausea, nervousness, unusual excitement
Less common or rare side effects may include:
- Anger/hostility, blurred vision, bone aches/pain, confusion, constipation, decreased concentration, depression, diarrhea, fast, fluttery heartbeat, incoordination, muscle pain/aches, numbness,
pain or weakness in hands or feet, rapid heartbeat, rash, restlessness, stomach and abdominal upset, sweating/clamminess, tingling or pins and needles, tremor, urinary incontinence, vomiting, weakness
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DRUG ABUSE AND DEPENDENCE :
Although BuSpar does not intensify the effects of alcohol, it is best to avoid alcohol while taking this medication.
If BuSpar is taken with certain other drugs, the effects of either can be
increased, decreased, or altered. It is especially important to check with your doctor before combining BuSpar with the following:
- The blood-thinning drug Coumadin
- Haloperidol (Hal
dol)
- MAO inhibitors (antidepressant drugs such as Nardil and Parnate)
- Trazodone (Desyrel)
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