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Cautions
Children¡XSerious side effects, such as convulsions (seizures), are more likely to occur in younger patients and would be of greater risk to infants than to older children or adults. In general, child
en are more sensitive to the effects of antihistamines. Also, nightmares or unusual excitement, nervousness, restlessness, or irritability may be more likely to occur in children.
Older adult
s¡XElderly patients are usually more sensitive to the effects of antihistamines. Confusion; difficult or painful urination; dizziness; drowsiness; feeling faint; or dryness of mouth, nose, or throat m
y be more likely to occur in elderly patients.
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How to Use
Follow the directions for using this medicine provided by your doctor. SWALLOW WHOLE. Do not break, crush, or chew before swallowing. Do not take this medicine with food. Do not take antacids containi
ng aluminum and magnesium within 2 hours of taking this medicine. STORE THIS MEDICINE at room temperature between 68 and 77 degrees F (20 and 25 degrees C) in a tightly-closed container. IF YOU MISS A
DOSE OF THIS MEDICINE and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT t
ake 2 doses at once.
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What is this medicine
Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They work by preventing the effects of a substance called histamine, which is produced by the body.
Histamine can cause itching, sneezing, runny nose, and watery eyes. Also, in some persons histamine can close up the bronchial tubes (air passages of the lungs) and make breathing difficult.
Some of the antihistamines are also used to prevent motion sickness, nausea, vomiting, and dizziness. In patients with Parkinson's disease, diphenhydramine may be used to decrease stiffness and tremor
s. Also, the syrup form of diphenhydramine is used to relieve the cough due to colds or hay fever.
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Side Effects of This Medicine
SIDE EFFECTS that may occur while taking this medicine include nausea, dry mouth, indigestion, nervousness, dizziness, trouble sleeping, or headache. If they continue or are bothersome, check with you
r doctor. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.
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Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include irregular or unusually slow or fast heartbeat, unusual nervousness or
excitement, rapid breathing, confusion, hallucinations, and seizures.
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Other Medicines
Anticholinergics (medicine for abdominal or stomach spasms or cramps)¡XSide effects, such as dryness of mouth, of antihistamines or anticholinergics may be more likely to occur
Erythromycin (e.g.
E-Mycin) or
Ketoconazole (e.g., Nizoral)¡XUse of these medicines with fexofenadine may cause an increased amount of fexofenadine in the blood.
Central nervous system (CNS) depressants (medi
ines that cause drowsiness)¡XEffects, such as drowsiness, of CNS depressants or antihistamines may be worsened; also, taking maprotiline or tricyclic antidepressants may cause some side effects of eit
er of these medicines, such as dryness of mouth, to become more severe
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