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Side Effects
Oral: (GI side effects reduced if take with meals)
Short-term therapy: nausea/vomiting, diarrhea, headache, dizziness, fatigue, skin rash, edema. inguinal adenopahty, anorexia, leg pain, medicatio
n taste, sore throat.
Long-term: nausea/vomiting, diarrhea, headache, vertigo, insomina, irritability, depression, skin rash, acne. accelerated hair loss, arthralgia, fever, palpitations, sore thr
oat, muscle cramps, mestrual abnormalities, lyphadenopathy.
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Other Medicines
Inform your doctor if you are taking any of the following:
- Lithium (e.g., Lithane) or
- Methotrexate or
- Other medicine for infection or
- Penicillamine (e.g., Cuprimine)
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What should I do if I forget a dose?
If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to
catch up.
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Other medical problems
Pregnancy¡XTopical acyclovir has not been studied in pregnant women. However, this medicine has not been shown to cause birth defects or other problems in animal studies using mice, rats, or rabbits,
xcept when given in very high doses in a study using rats.
Breast-feeding¡XIt is not known whether topical acyclovir passes into the breast milk. However, acyclovir ointment has not been repo
ted to cause problems in nursing babies, even though small amounts of topical acyclovir are absorbed through the mother's skin and mucous membranes. Although most medicines pass into breast milk in sm
all amounts, many of them may be used safely while breast-feeding.
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What Is It
Acyclovir (ay-SYE-kloe-veer) belongs to the family of medicines called antivirals. Antivirals are used to treat infections caused by viruses. Usually they work for only one kind or group of virus infe
ctions.
Topical acyclovir is used to treat the symptoms of herpes simplex virus infections of the skin, mucous membranes, and genitals (sex organs). Although topical acyclovir will not cure
herpes simplex, it may help relieve the pain and discomfort and may help the sores (if any) heal faster. Topical acyclovir may also be used for other conditions as determined by your doctor.
Acyclovir is available only with your doctor's prescription, in the following dosage forms:
Topical
Cream (Canada)
Ointment (U.S. and Canada)
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Proper Use of This Medicine
Genital herpes (initial): 200mg po q 4 hours 5 times/day X 10 days
Genital herpes (recurrent or suppressive therapy): 400mg 2 times/day for up to 12 months, then re-evaluate.
Herpes zoster: 80
0mg 5 times/day X 7-10 days
Sever HZV or complications: 5-10mg/kg IV q 8 hours X 7-10 days. Administer at constant rate over 1 hour.
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