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Precautions
If you are or may be pregnant, check with your doctor for instructions on using this medicine during pregnancy.

Possible food and drug interactions when taking this medication
Tell you doctor if you are taking any of the following:
- Deferoxamine (e.g., Desferal) (with long-term use) or
- Gold salts (medicine for arthritis) or
- Inflammation or pain medicine

Side Effects of This Medicine
This medication may cause stomach upset, loss of appetite, nausea, vomiting, diarrhea, headache, dizziness or weakness. These effects should disappear in a few days as your body adjusts to the medicat ion. If they persist or become worse, inform your doctor. Notify your doctor if you experience: numbness or tingling of the hands or feet, leg pain, sore throat, skin rash, change in the amount of uri ne. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. I f you notice other effects not listed above, contact your doctor or pharmacist.

Other medical problems
This medication should be used cautiously during pregnancy only if clearly needed. It is not known if this medication appears in breast milk. Consult with your doctor before breast-feeding.
Avoid s exual activity while signs and symptoms of genital herpes are present to prevent infecting your partner. Inform your doctor if this medication does not appear to decrease the frequency or severity of recurrent infections.

Why is this drug prescribed?
Acyclovir (ay-SYE-kloe-veer) belongs to the family of medicines called antivirals. Antivirals are used to treat infections caused by viruses. Usually they work for only one kind or group of virus infe ctions.

Topical acyclovir is used to treat the symptoms of herpes simplex virus infections of the skin, mucous membranes, and genitals (sex organs). Although topical acyclovir will not cure herpes simplex, it may help relieve the pain and discomfort and may help the sores (if any) heal faster. Topical acyclovir may also be used for other conditions as determined by your doctor.

Acyclovir is available only with your doctor's prescription, in the following dosage forms:

Topical
Cream (Canada)
Ointment (U.S. and Canada)

How to Use
Genital herpes (initial): 200mg po q 4 hours 5 times/day X 10 days
Genital herpes (recurrent or suppressive therapy): 400mg 2 times/day for up to 12 months, then re-evaluate.
Herpes zoster: 80 0mg 5 times/day X 7-10 days
Sever HZV or complications: 5-10mg/kg IV q 8 hours X 7-10 days. Administer at constant rate over 1 hour.


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