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What Is It
Acyclovir is used to treat herpes infections of the skin, lip, and genitals; herpes zoster (shingles); and chickenpox. It does not cure herpes infections but decreases pain and itching and promotes he aling.

Topical acyclovir does not prevent the recurrence of sores but may decrease pain and itching if applied when the earliest symptoms first appear. Oral acyclovir decreases the frequency and severity of recurrent sores, but it is used only by people with severe herpes infections because of possible adverse effects.

Special warnings about this medication
Category C. Risk to fetus cannot be ruled out. Consider use if benefit outweighs the potential risk. Exposure registry is available: 1-800-722-9292, ext. 58465 (note: this number is no longer used for antiretroviral drugs. See Health Maintenance section for the pregnancy protocols which contain the antiretroviral registry number.)

Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include sluggishness, change in amount of urine, loss of consciousness ¡K

Possible food and drug interactions when taking this medication
It is especially important that your health care professional know if you are taking any of the following:
- Carmustine (e.g., BiCNU) or
- Cisplatin (e.g., Platinol) or
- Combination pa in medicine containing acetaminophen and aspirin (e.g., Excedrin) or other salicylates or
- Cyclosporine (e.g., Sandimmune) or
- Deferoxamine (e.g., Desferal) (with long-term use) or
- Gold salts (medicine for arthritis) or
- Inflammation or pain medicine, except narcotics, or
- Lithium (e.g., Lithane) or
- Methotrexate (Mexate) or
- Other medicine for infection or
- Penicillamine (e.g., Cuprimine) or
- Plicamycin (e.g., Mithracin) or

What should I do if I forget a dose?
If you are using tablets, capsules, or liquid, take the missed dose as soon as you remember it and take any remaining doses for that day at evenly spaced intervals.

If you are using ointment, apply it as soon as you remember and apply further doses at your regular interval (e.g., every 3 hours) until you go to bed.

However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of either the ointment or oral medication to make up for a missed one.

What special precautions should I follow?
If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

The areas affected by herpes, chickenpox, or shingles should be kept as clean and dry as po ssible. Also, wear loose-fitting clothing to avoid irritating the sores (blisters).

It is important to remember that acyclovir will not keep you from spreading herpes to others.


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